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Ovarian cyst

An ovarian cyst is a fluid-filled mass that can occur in one or both ovaries. 

Under normal conditions, each menstrual cycle produces a physiological cystic structure – the follicle – in the ovary, which matures into an egg. After ovulation (the release of an egg from the ovary), the corpus luteum forms in place of the follicle. Such changes are physiological and occur cyclically every month. They are also clearly visible on gynaecological ultrasound and are not considered pathological changes.

However, other types of cysts can form in the ovaries – both benign and malignant. This article will discuss benign ovarian cysts. Some ovarian cysts are linked to menstrual cycle irregularities, while others form on their own when certain ovarian cells don’t develop as they should.

Although these cysts are benign and often asymptomatic, regular monitoring is recommended, with early treatment if necessary. Complications such as cyst rupture or torsion can cause sudden, severe symptoms, and require urgent surgical treatment.

What types of benign cysts exist, and how do they arise?

Functional ovarian cysts

Such cysts depend on the menstrual cycle and occur as a result of its disruption.

Follicular ovarian cysts

They occur when ovulation, or the release of an egg, has not taken place, and the follicle containing the egg continues to grow.

Corpus luteum cysts

They occur when ovulation has occurred, but fluid continues to accumulate inside the cyst.

Functional cysts rarely cause symptoms and resolve on their own within a few menstrual periods.

Other ovarian cysts

The formation of such cysts is independent of the menstrual cycle. Here are the most common types of such cysts.

Ovarian dermoid cyst or teratoma

A cyst that forms from embryonic tissue. They often contain fat, skin, hair, teeth, bone, and cartilage fragments. 0.2–2% of these cysts may be malignant.

Cystadenoma

A benign ovarian cyst that forms on the surface of the ovary and contains a mucus-like fluid. They can reach very large sizes, which may make it impossible to preserve normal ovarian tissue.

Endometrioma (endometriotic cysts)

These cysts develop from tissue similar to the uterine lining (endometrium) that grows on the ovary, gradually forming a cyst filled with a chocolate-like fluid. Find more information about endometriotic cysts here.

Endometriotic cysts
Endometriotic cysts

All benign cysts can grow to a large size and cause significant symptoms, particularly if they undergo torsion, which cuts off the ovary’s blood supply and may necessitate removal if surgery is not performed promptly.

Although the cysts described above are benign and only rarely become malignant, the only definitive way to determine their nature is surgical removal and histological examination under a microscope. If a new ovarian mass develops during menopause, careful evaluation is essential, as the likelihood of malignancy is higher.

What are the symptoms of ovarian cysts?

Symptoms depend on the size of the cyst and can vary widely. In the case of benign cysts, symptoms will be more pronounced when the cysts are larger in size. The only exception is endometriotic cysts, which, even when small in size, can cause severe symptoms.

Possible symptoms:

  • pain of a different nature – pulling ache, sometimes sudden – in attacks, pronounced on the side where the cyst is located;
  • tight or heavy feeling in the abdomen;
  • bloating.

If you know you have a cyst and suddenly experience severe pain or vomiting, you should seek emergency medical help immediately.

What are the possible complications of ovarian cysts?

The potential complications of benign cysts are one of the main reasons for their timely treatment.

Ovarian torsion

The ovary is about 3–4 cm in size and is fixed by ligaments that lead blood vessels to the ovary. In the normal range, as well as with small cysts, the ovary moves freely. When an ovary contains a larger cyst, there is a risk of torsion, where the ovary twists and compresses its blood vessels, cutting off the blood supply. As a result, the ovarian tissue dies.

Rupture of an ovarian cyst (haemorrhagic cyst)

This can happen on its own or as a result of trauma, for example, during intercourse. The larger the cyst, the greater the risk of rupture. If the cyst ruptures, there is a risk of internal bleeding, and urgent surgical treatment may be needed.

How is an ovarian cyst diagnosed, and what additional tests may be needed?

The best way to diagnose ovarian cysts is a gynaecological ultrasound. Ultrasound is a quick and accessible method that not only identifies and measures cyst size but also determines the cyst type with high accuracy. Studies have shown that ultrasound can distinguish benign from malignant cysts with high accuracy by identifying the specific features of each type.

Additional diagnostic tests

  • Pregnancy test – to rule out a possible ectopic pregnancy, which may be visible on an ultrasound as a cystic mass near the ovary.
  • Blood tests – in unclear cases, markers of ovarian cancer such as CA125, HE4 and others need to be detected. They can help distinguish benign from malignant cysts, but it should be remembered that these markers are not specific and may also be elevated in the case of benign conditions. For example, CA125 is often increased in endometriosis.
  • Magnetic resonance imaging and computed tomography – these additional tests are needed if a malignant ovarian tumour is suspected.

What treatment is required for ovarian cysts and when?

As mentioned above, the vast majority of cysts, especially functional cysts, do not require treatment. They often disappear during 2–3 menstrual cycles. “However, watchful waiting is not always appropriate – it is important to assess both the size and symptoms of the cyst, while also considering the woman’s age.

Cyst monitoring

This approach is appropriate if the cyst is asymptomatic and the ultrasound shows no suspicious features of malignancy. In such cases, a follow-up gynaecological ultrasound is required to monitor changes in the cyst’s size and appearance.

Hormonal therapy

Although this method is often used as a treatment, it is unlikely to reduce the size of existing cysts. Cysts may disappear independently of taking contraceptive medications. Hormonal therapy is a good method for preventing cysts from recurring in women who have them more often.

Surgical treatment of an ovarian cyst

Surgery is the main treatment for ovarian cysts that cause symptoms, have uncertain characteristics, persist for several months, or when malignancy is suspected. Depending on the cyst’s size, type, and the woman’s age, either conservative (ovary-sparing) or radical treatment may be appropriate.

Sparing treatment of ovarian cyst

During the procedure, only the cyst is removed, and the rest of the ovarian tissue is preserved. This approach is possible in cases where no malignancy is suspected.

Radical treatment of ovarian cyst

In this case, the remaining ovarian tissue is removed together with the cyst. This approach is particularly indicated in menopausal women, when malignancy is suspected, when normal ovarian tissue cannot be preserved, or to prevent cyst recurrence.

Most benign ovarian cysts, even large ones, are treated laparoscopically – the entire operation is performed through 3–4 small abdominal incisions. After the cyst is removed or the ovary is detached, the tissue is placed in a special pouch and extracted through a small abdominal incision. Next, the cyst capsule is pierced and the contents suctioned out. This way, the contents of the cyst do not enter the abdominal cavity and cysts larger than 10 cm can be pulled out through a small hole of 1 cm.


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